PHYSIOLOGICAL AND MOLECULAR GENETIC EFFECTS OF TIME-VARYING ELECTROMAGNETIC FIELDS ON HUMAN NEURONAL CELLS (a)


Pulsed Electromagnetic Healing Developments

Dr. Gordon spoke on exploring the limits of pulsed electromagnetic healing. This technology uses very fast (8 nanosecond) pulses of electromagnetic energy to help the body heal. Dr. Gordon stated he was the first physician in the US to use pulsed electromagnetic fields (PEMF) on soft tissues in humans. The technology has been studied by NASA at the LBJ Center and written about by Tom Goodwin. Another quoted reference was The Body Electric by Robert O. Becker. Since the 1980’s, PEMFs have been used in Russia and Hungary and now are used worldwide. The United States is the only major industrial country not currently using PEMFs.

In 1980, his team received the first investigational device exemption issued in the US to study low level laser effects in soft tissue injuries. After physicists convinced them that the light was not penetrating the tissue, they went on to show that a pulsed EM field of slower frequencies than the laser light could be responsible for the results they were seeing. This led to the development of the hand-held battery operated device Dr. Gordon demonstrated at the conference. The device retails for around $200 USD.
They investigated different wave forms including sine-wave, square-wave, and dc triangle pulses. They found that that best results came from very fast nanosecond pulses with high bio efficiency rates of change.
He reported the pulsed EM fields would stimulate neurons to grow faster. It also helped to line up the body’s natural antioxidants with free radicals to neutralize them much more rapidly. Free radicals have a role in aging, illness, and death; and antioxidants help counter free radicals. Stopping free radicals stops inflammation. “Healing won’t take place until inflammation stops,” he said. Dr. Gordon cited several scientific papers from mainstream journals that have documented that the EM pulses accelerate healing by acting as a catalyst to correct the alignment, making it easier for the antioxidants to connect with the free radicals.
Dr. Gordon also spoke of the first critical 12 hours in a “stunning” situation in which a person is on the brink of death. During that time, the body has to call upon what he calls a “constitutive response” – based on what is present –whereas after that first 12 hours, the body has had time to produce additional elements, called the “transcriptive response,” being transcribed from the DNA and produced into building blocks of regeneration and healing.
Thus, the most crucial time in which the PMF technology can make the most difference – even life and death, is in the first 12 hours in which the PMF can help the body manage the overwhelming release of free radicals as a result of the stunning trauma. He also addressed the phenomenon of stress from a physiological perspective, citing that the mitochondria cranks out free radicals when in a stress situation.
His apparatus showed a 40% increase in growth hormones by controlling the electron spin in free radicals. He said it has been measured to penetrate the skin 4-5 cm but that there could be other phenomenon at work because he is seeing effects clinically much deeper than that. He has treated over 20,000 patients using this technology. Dr. Gordon cited a Stanford study that showed “onboard antioxidants 100 times more effective”. It can treat inflammation, illness, and aging symptoms with no side effects.
Several times in his presentation he recommended a recent review by NASA compiled over 4 years with $3.5 million dollars in funding that he called a “watershed paper” on the subject.
He states his frustration with the politics of the American Medical Association and the U.S. Drug Lobby who have stonewalled this technology from being able to achieve acceptance by the mainstream of U.S. medicine. There are 2.5 million deaths a year from hospital-administered drugs. 200,000 of those are from gastric bleeding.
Dr. Gordon believes the Electromagnetic Pulse technology may eventually nearly eliminate the need for the pharmacological industry.
At the conference, he demonstrated the device and answered questions from the audience. One attendee asked if it is possible that approaches like Reiki work because they impose from one person to another the appropriate electromagnetic stimulus. He replied that “phenomenologically” he would tend to see credence in this hypothesis, though he knows of no hard evidence to support it.
He attended the entire event and was found often in congenial conversation with various conference-goers. After his presentation, he told a group about a personal application of the technology. He said he a massive heart attack several years ago – five valve bypass. Soon thereafter, his doctors told him that he needed a transplant or he would be gone. He put the PEMF device in his pocket next to his heart, and he never had the transplant. Later he did a 2,500 mile solo bicycle trip to show himself and the world that he was healed. He’s gearing up now for another trip.

source  http://www.pureenergysystems.com/

 

Abstract
The present investigation details the development of model systems for growing two- and threedimensional
human neural progenitor cells within a culture medium facilitated by a time-varying  electromagnetic field (TVEMF). The cells and culture medium are contained within a two- or  three-dimensional culture vessel, and the electromagnetic field is emitted from an electrode or coil. These studies further provide methods to promote neural tissue regeneration by means of  culturing the neural cells in either configuration. Grown in two dimensions, neuronal cells  extended longitudinally, forming tissue strands extending axially along and within electrodes  comprising electrically conductive channels or guides through which a time-varying electrical
current was conducted. In the three-dimensional aspect, exposure to TVEMF resulted in the  development of three-dimensional aggregates, which emulated organized neural tissues. In both  experimental configurations, the proliferation rate of the TVEMF cells was 2.5 to 4.0 times the  rate of the non-waveform cells. Each of the experimental embodiments resulted in similar
molecular genetic changes regarding the growth potential of the tissues as measured by gene chip  analyses, which measured more than 10,000 human genes simultaneously.

Background
Since the 1980s, many methods have been employed in an attempt to accomplish the  regeneration of neuronal tissues. Hinkle et al. (1980) detailed the directional growth of frog  neurons in an electric field applied by inducing direct DC voltage. Similarly, researchers both  nationally and internationally have employed DC electric fields externally and internally as  implants to stimulate the direct regeneration of nerve cells in a variety of animal tissues (Borgens  et al. 1981,1986, 1986a, 1990, 1997).
These studies have met with limited success, but have shown the potential efficacy of using the inherent characteristics of neural cells to achieve their regeneration. All of these studies incorporate the inclusion of electrodes in direct contact with the tissue of interest.
Other studies have shown that electrically charged polymeric substrates may have value in the  stimulation of the regenerative process (Valentini et al., 1992; Makohliso et al., 1992).
Additionally, Borgens et al. (1994) substantiates the inference that low-level electric fields and  physiological voltage gradients are of importance. However, continuing investigation in these areas has indicated the possibility of a missing component to complete the valuable work of  previous investigations. The missing component may well be the addition of a magnetic element.
Combining the electric and magnetic elements would seem logical, but to date may not have been employed due to traditional purist approaches to experimentation. The current studies are a  composite of physiology and electromagnetic bioengineering, which relate generally to the fields  of biophysics, tissue regeneration, tissue culture, and neurobiology. The present investigation
relates to the use of a time-varying electromagnetic field for potentiation of the growth of  mammalian cells and tissues. The preferred protocol uses two-dimensional conducting plate  electrodes and may be applied to conventional two-dimensional tissue cultures or to three dimensional  tissue cultures. One may achieve three-dimensional cultures either by exposure to actual microgravity or by using rotating wall vessel (RWV) technology, which simulates some of  the physical conditions of microgravity (Goodwin et al., 1993c). The time-varying electromagnetic field is achieved in the vicinity of the electrode by passing a time-varying current pulse with modulated signal through the electrode.
Growth of a variety of both normal and neoplastic mammalian tissues in both mono-culture and  co-culture has been established in both batch-fed and perfused RWVs (Schwarz et al., 1991a,1991b), and in conventional plate or flask-based culture systems. In some applications, growth  of three-dimensional tissues in these culture systems has been facilitated by support of a solid
matrix of biocompatible polymers and microcarriers. In the case of spheroidal growth, three  dimensional  structure has been achieved without matrix support (Goodwin et al., 1992, 1993a, 1993b, 1997). The NASA RWV tissue culture technologies have extended this three dimensional  capacity for a number of tissues and have allowed the tissue to express different  genes and biomolecules. Neuronal tissue has been largely refractory, in terms of controlled  growth induction and three-dimensional organization, under conventional culture conditions.
Actual microgravity, and to a lesser extent, rotationally simulated microgravity, have permitted  some enhanced nerve growth (Lelkes and Unsworth, 1997). Previous attempts to electrically  stimulate growth have used static electric fields, static magnetic fields, and the direct passage of  current through the culture medium, but not the induction of an AC time-varying electromagnetic
field in the culture region.
Neuronal tissue comprises elongated nerve cells composed of elongated axons, dendrites, and  nuclear areas. Axons and dendrites are chiefly responsible for transmission of neural signals over distance. Longitudinal cell orientation is critical for proper tissue formation and function.
The nucleus plays the typical role of directing nucleic acid synthesis for the control of cellular  metabolic function, including growth. In vivo, the neuronal tissue is invariably spatially associated with a system of feeder, or glial, cells. This three-dimensional spatial arrangement has  not been reproduced by conventional in vitro culture.

Investigators (Borgens et al., Valentini et al., and others) have used static electric fields in an  attempt to enhance nerve growth in culture with some success to either alter embryonic  development or achieve isolated nerve axon directional growth, but have not yet achieved actual  control mechanisms for potentiation of growth or genetic activity causing growth. Mechanical  devices intended to help grow and orient three-dimensional mammalian neuronal tissue are  currently available. Fukuda et al. used zones formed between stainless steel shaving blades to  orient neuronal cells or axons. Additionally, electrodes charged with electrical potential were  employed to enhance axon response. Aebischer described an electrically charged, implantable  tubular membrane for use in regenerating severed nerves within the human body.
None of these devices uses channels of cell-attractive material, nor do they apply a time-varying  electromagnetic field, a static electrical, or a static magnetic field. Additionally, no use is made  of simulated or actual microgravity techniques for pure neuronal or mixed neuronal and feeder  cell cultures. Incorporation of an electromagnetic stimulus in conjunction with growing threedimensional  mammalian neuronal tissue in the proximity of, or directly upon the surface of, a  current-carrying electrode (which may be bioattractive and directly adherent to the cells) is  expected to enhance the proliferative response. Furthermore, the use of a time-varying current to  induce a corresponding time-varying electromagnetic field in the vicinity of the growing culture  to potentiate or spatially direct cell growth is not part of the prior art.

(TO BE CONTINUED)

Thomas J. Goodwin, Ph.D.
Lyndon B. Johnson Space Center / 2003

About sooteris kyritsis

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